邮箱：202202002@bucm.edu.cn
个人简介
李硕硕 北京中医药大学生命科学学院特聘副教授。入选2025年“高创计划”青年人才托举工程项目、北京中医药大学卓越新锐青年人才。在Advanced Science、British Journal of Pharmacology、Journal Neuroinflammation等国际知名杂志发表研究论文22篇。获批主持国家自然基金委青年项目、北京市面上等项目。
研究方向
神经系统疾病机制及中医药干预
主要成果
1. Yuan, T., Wang, T., Li, S., Wei P., Wang L., Pan, B., Hu, J., Wu, S., Shen, Y., Yuan, Z. & Wu H. (2025) Innovating transcranial magnetic stimulation treatment for post-traumatic stress disorder: Zapping away the bad memory. Fundamental Research, (共一)
2. Zhang, X., Zhang, P., Zhang, C., Yuan, Z., & Li, S. (2025) Hypoxia-mediated regulation of mRNA metabolism: from transcription to stability. Cell Commun Signal. 23(1):467. (共通讯)
3. Zhang, Y., Che, N., Wang, B., Liu, S., Dong, Y., Kong, X., Yun, Y., Li, S., Tang, XQ., & Liao, Y. (2025) 1,2,4-Trimethoxybenzene ameliorates depression-like behaviors by inhibiting the activation of NLRP3 inflammasome. Int Immunopharmacol. 151:114361. (共通讯)
4. Li, S., Hu, W., Gong, S., Zhang, P., Cheng, J., Wang, S., Wang, Y., Shi, W., Li, Q., Wang, F., & Yuan, Z. (2023). The Role of PRRC2B in Cerebral Vascular Remodeling Under Acute Hypoxia in Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 10(25), e2300892.（共一、共通讯）
5. Zhang, P., Gong, S., Li, S., & Yuan, Z. (2023). PVT1 alleviates hypoxia-induced endothelial apoptosis by enhancing autophagy via the miR-15b-5p/ATG14 and miR-424-5p/ATG14 axis. Biochemical and biophysical research communications, 671, 1–9. （共通讯）
6. Li, S., Liao, Y., Dong, Y., Li, X., Li, J., Cheng, Y., Cheng, J., & Yuan, Z. (2021). Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice. Journal of neuroinflammation, 18(1), 7.
7. Li, S., Li, J., Pan, R., Cheng, J., Cui, Q., Chen, J., & Yuan, Z. (2021). Sodium rutin extends lifespan and health span in mice including positive impacts on liver health. British journal of pharmacology, 10.1111/bph.15410. Advance online publication.