个人简介
杨明锐，女，医学博士，北京中医药大学讲师，硕士生导师。毕业于武汉大学病毒学国家重点实验室，中国科学院生物大分子国家重点实验室联合培养。任中华中医药学会感染病分会青年委员。主持国家自然科学基金1项、北京中医药大学竞争类科研项目2项，参与多项国家级及省部级课题。
研究方向
中医药免疫调节防治肺脏疾病的机制研究
主要成果
代表性论文：
[1] Chen Y*, Yang M*, Hua Q#. Artificial intelligence in central-peripheral interaction organ crosstalk: the future of drug discovery and clinical trials. Pharmacol Res, 2025, 215:107734.
[2] Zhao M*, Deng D, Liu H, Guo R, Wu J, Hao Y#, Yang M#. Berberine Suppresses Influenza A Virus-Triggered Pyroptosis in Macrophages via Intervening in the mtROS-MAVS-NLRP3 Inflammasome Pathway. Viruses, 2025, 17(4):539.
[3] Liu T*, Hao Y, Mao Q, Zhou N, Liu M, Wu J, Wang Y, Yang M#. Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy. Chin J Integr Med, 2025, 31(1):19-27.
[4] Li Y*, Yang M*, Nan Y*, Wang J, Wang S, Cui D, Guo J, He P, Dai W, Zhou S, Zhang Y, Ma W#. SARS-CoV-2 spike host cell surface exposure promoted by a COPI sorting inhibitor. Acta Pharm Sin B, 2023, 13(7):3043–53.
[5] Yang M*, Ma L*, Su R, Guo R, Zhou N, Liu M, Wu J, Wang Y#, Hao Y#. The Extract of Scutellaria baicalensis Attenuates the Pattern Recognition Receptor Pathway Activation Induced by Influenza A Virus in Macrophages. Viruses, 2023, 15(7):1524.
[6] Yang M*, Feng F, Liu Y, Wang H, Yang Z, Hou W#, Liang H#. pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating. J Gen Virol, 2016, 97(9):2149-2156.
[7] Xing M*, Yang M*, Huo W*, Feng F, Wei L, Jiang W, Ning S, Yan Z, Li W, Wang Q, Hou M, Dong C, Guo R, Gao G, Ji J, Zha S, Lan L, Liang H, Xu D#. Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun, 2015, 6:6233.
[8] 代文欣*,马文福,王佳铭,马璐瑶,郝钰,吴珺#,杨明锐#.痰热清注射液对脂多糖诱导小鼠结肠损伤及肠道菌群的影响.医学研究杂志,2024,53(12):130-135+109.
[9] 杨明锐*,华茜#.新型冠状病毒导致神经损伤的研究进展及中医药治疗价值.中华中医药学刊,2022,40(11):20-23.
[10] 南亚楠*,李亚东,吴珺,郝钰,杨明锐#.小檗碱对流感病毒感染小鼠肺与结肠损伤的保护作用研究.中国免疫学杂志,2021,37(09):1069-1073+1081.